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Author Question: Myoclonal epilepsy and ragged red fiber disease (MERRF) is a human condition named for the ragged ... (Read 80 times)

jazziefee

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Myoclonal epilepsy and ragged red fiber disease (MERRF) is a human condition named for the ragged red fibers of skeletal muscle cells and myoclonic epilepsy in affected individuals. People with this disorder have a mutation in a mitochondrial gene for a tRNA, specifically that for lysine. Affected individuals are heteroplastic. Why?
◦ Interference with translation is not fully rescued by importing lysine from the cytoplasm.
◦ Homoplastic organelles would be inviable due to failures in translation.
◦ Lysine is required in translation of every one of the mitochondrial genes.
◦ Mutations of this gene affect individuals before birth.
◦ Mutations of this gene are dominant.


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Marked as best answer by jazziefee on Jan 12, 2022

amandanbreshears

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jazziefee

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Reply 2 on: Jan 12, 2022
YES! Correct, THANKS for helping me on my review


nathang24

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Reply 3 on: Yesterday
Excellent

 

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