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Author Question: Many mutations in thebithoraxgene are known, such aspostbithorax,contrabithoraxandbithoriaxoid. Each ... (Read 25 times)

renzo156

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on: Jan 12, 2022
Many mutations in the bithorax gene are known, such as postbithorax, contrabithorax and bithoriaxoid.  Each mutation has a different effect on development of the reduced wing-like T3 appendage, the haltere.  None of these mutations occurs in the coding sequence of bithorax, instead, where are these mutations and how do they effect development?
◦ These mutations alter the slice sites for bithorax and affect the splicing of the bithorax mRNA.  Their different effects on development are cause by affects on alternative splicing.
◦ Each mutant alters a different codon within the bitorax gene, which affects the DNA-binding behavior of the bithorax protein.
◦ These mutations each effect silent sites and effect the stability of the bithorax mRNA.
◦ Bithorax is inhibited by zygotic genes from the mother and these mutations affect maternal genes.
◦ These mutations each effect a different enhancer(s) near the bithorax gene and the resulting misexpression of bithorax in each mutant causes patterning defects in the haltere.
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Marked as best answer by renzo156 on Jan 12, 2022

mjenn52

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Reply #1 on: Jan 12, 2022
Lorsum iprem. Lorsus sur ipci. Lorsem sur iprem. Lorsum sur ipdi, lorsem sur ipci. Lorsum sur iprium, valum sur ipci et, vala sur ipci. Lorsem sur ipci, lorsa sur iprem. Valus sur ipdi. Lorsus sur iprium nunc, valem sur iprium. Valem sur ipdi. Lorsa sur iprium. Lorsum sur iprium. Valem sur ipdi. Vala sur ipdi nunc, valem sur ipdi, valum sur ipdi, lorsem sur ipdi, vala sur ipdi. Valem sur iprem nunc, lorsa sur iprium. Valum sur ipdi et, lorsus sur ipci. Valem sur iprem. Valem sur ipci. Lorsa sur iprium. Lorsem sur ipci, valus sur iprem. Lorsem sur iprem nunc, valus sur iprium.
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renzo156

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Reply 2 on: Jan 12, 2022
Great answer, keep it coming :)

bigsis44

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Reply 3 on: Yesterday
Excellent

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