Question 1
Which of the SN2 reactions below is expected to proceed the rapidly?
◦ CH
3CH
2CH
2Br + NaOH in DMSO
◦ CH
3CH
2CH
2Br + NaOH in acetone
◦ CH
3CH
2CH
2Br + NaOH in ethanol
◦ A and B
◦ B and C
Question 2
Why are SN1 reactions favored by polar protic solvents?
◦ Polar protic solvents cannot form hydrogen bonds.
◦ Polar protic solvents stabilize intermediates.
◦ Polar protic solvents stabilize the nucleophile.
◦ Polar protic solvents contribute leaving groups.