Question 1
Which of the choices is a reactive starting material in the Claisen condensation?
◦ propanoic anhydride
◦ butanal
◦ 3-pentanone
◦ 1-propanol
◦ ethyl butanoate
Question 2
Why shouldn't CH
3ONa be used for Claisen condensation of ethylbutanoate?
◦ Using CH
3ONa will yield a transesterification product.
◦ Ammonium chloride would be required for the reaction to take place.
◦ The starting ester will undergo hydrolysis.
◦ There will be no reaction.
◦ The reaction will proceed too quickly.