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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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Medication errors are three times higher among children and infants than with adults.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Adults are resistant to the bacterium that causes Botulism. These bacteria thrive in honey – therefore, honey should never be given to infants since their immune systems are not yet resistant.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.