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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.