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Opium has influenced much of the world's most popular literature. The following authors were all opium users, of varying degrees: Lewis Carroll, Charles, Dickens, Arthur Conan Doyle, and Oscar Wilde.
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Illicit drug use costs the United States approximately $181 billion every year.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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Persons who overdose with cardiac glycosides have a better chance of overall survival if they can survive the first 24 hours after the overdose.
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More than 4.4billion prescriptions were dispensed within the United States in 2016.