Question 1
Most mutations that affect RNA splicing are:
◦ deletions in the central portion of introns.
◦ single-base deletions at intron-exon junctions.
◦ single-base insertions at intron-exon junctions.
◦ single-base substitutions at intron-exon junctions.
◦ single-base substitutions within an adjacent exon.
Question 2
Which of the following is an example of the “genome phenotype?”
◦ A gene can produce more than one polypeptide product.
◦ Genes are transcribed into RNAs that serve important functions.
◦ A DNA sequence is under constraint to allow better folding of the DNA.
◦ Messenger RNAs are translated into polypeptides.
◦ The enzyme product of a gene facilitates development of a trait.