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Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.
When intravenous medications are involved in adverse drug events, their harmful effects may occur more rapidly, and be more severe than errors with oral medications. This is due to the direct administration into the bloodstream.