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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The horizontal fraction bar was introduced by the Arabs.
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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.
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The most destructive flu epidemic of all times in recorded history occurred in 1918, with approximately 20 million deaths worldwide.