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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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Inotropic therapy does not have a role in the treatment of most heart failure patients. These drugs can make patients feel and function better but usually do not lengthen the predicted length of their lives.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
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Malaria mortality rates are falling. Increased malaria prevention and control measures have greatly improved these rates. Since 2000, malaria mortality rates have fallen globally by 60% among all age groups, and by 65% among children under age 5.