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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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There are 60,000 miles of blood vessels in every adult human.
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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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Hyperthyroidism leads to an increased rate of metabolism and affects about 1% of women but only 0.1% of men. For most people, this increased metabolic rate causes the thyroid gland to become enlarged (known as a goiter).
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.