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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
An identified risk factor for osteoporosis is the intake of excessive amounts of vitamin A. Dietary intake of approximately double the recommended daily amount of vitamin A, by women, has been shown to reduce bone mineral density and increase the chances for hip fractures compared with women who consumed the recommended daily amount (or less) of vitamin A.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
Thyroid conditions may make getting pregnant impossible.
The shortest mature adult human of whom there is independent evidence was Gul Mohammed in India. In 1990, he was measured in New Delhi and stood 22.5 inches tall.

