Answer to Question 1
Macrovascular changes: There is an increased risk for arteriosclerosis, resulting in poor circulation and vascular complications such as stroke, heart attack, and gangrene of the legs. These are caused by abnormalities in fat metabolism and increased lipid levels in the blood.
Microvascular changes: Retinal capillaries undergo degenerative changes, eventually leading to blindness; glomerular arterioles and capillaries of the kidneys also undergo degenerative changes, resulting in glomerulosclerosis, impairing the blood flow to the glomeruli and tubules. This leads to the progressive impairment of renal function and eventually to renal failure. With glomerular damage, protein leaks out resulting in nephrotic syndrome; peripheral nerves undergo degenerative changes resulting in peripheral neuritis characterized by pain and impaired sensation in the extremities.
Answer to Question 2
B