Author Question: Which of the following endocrine functions are responsible for increased resorption of bone that ... (Read 417 times)

beccaep · **on:** Jun 25, 2018

Which of the following endocrine functions are responsible for increased resorption of bone that results in a reduction of the number and function of osteoclasts? Select all that apply.

A)
Calcitonin secretion
B)
Decrease in estrogen levels
C)
Stimulation of excess thyroid hormone
D)
Release of catecholamines
E)
Increase movement of calcium and phosphate from bone into the extracellular fluid

Question 2

A 23-year-old woman has been referred to a fertility clinic after 1 year of attempting to become pregnant. Her diagnostic workup has resulted in a diagnosis of polycystic ovary syndrome (PCOS).

What will the first line of treatment most likely consist of?
A)
Estrogen-progesterone hormone therapy and the administration of clomiphene
B)
Surgical resection of the ovaries using laparoscopy
C)
Lifestyle modifications to include weight loss by lowering calories and fat consumption
D)
Temporary use of oral contractive agents

sarah_brady415 · **Reply #1 on:** Jun 25, 2018

Answer to Question 1

Ans:
A, B

Feedback:

Parathyroid hormone increases the number of resorptive function of the osteoclasts. Calcitonin is thought to reduce the number and resorptive function of the osteoclasts. Estrogen also reduces the number and function of the osteoclasts. Thus, the decrease in estrogen levels that occurs at menopause results in increased resorption of bone. Release of catecholamines has no influence over osteoclast function. Increased movement of calcium and phosphate from bone into extracellular fluid is regulated by parathyroid hormone.

Answer to Question 2

Ans:
C

Feedback:

Lifestyle modifications are the treatment of choice for PCOS. Hormone therapy, surgery, and use of oral contraceptives are less likely to be a primary treatment option.