Patients who have a deficiency of protein C or protein S have ...

[biggirl4568]

Patients who have a deficiency of protein C or protein S have which type of disorder?
 
  a. Bleeding disorder
  b. Thrombotic disorder
  c. Bruising disorder
  d. Hypercalcemia

Question 2

On what does factor VIII depend for stability?
 
  a. VWF
  b. Platelets
  c. Thrombin
  d. Protein S

[diana chang]

Answer to Question 1

ANS: B
Patients with a deficiency of either protein C or protein S have a thrombotic disorder. These two proteins are important in regulating, by downgrading, thrombin generation and thus clotting. Activated protein C binds free protein S to form a complex that inactivates factors Va and VIIIa.

Answer to Question 2

ANS: A
Factor VIII circulates bound to VWF. Free factor VIII is unstable in plasma, so much so that it cannot even be detected.

[biggirl4568]

Thanks for the timely response, appreciate it

[alvinum]

Great answer, keep it coming