This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Which of the following is a positive predictive factor in children with precursor B-ALL? a. High ... (Read 53 times)

fagboi

  • Hero Member
  • *****
  • Posts: 535
on: Jun 25, 2018
Which of the following is a positive predictive factor in children with precursor B-ALL?
 
  a. High leukocyte count; less than 1 year of age
  b. Low leukocyte count; 4-10 years of age
  c. High leukocyte count; PBX1/E2A translocation
  d. Hyperdiploid chromosomes, high leukocyte count, less than 1 year of age

Question 2

Name the classifications of ALL, and explain how they differ in molecular analysis and immunophenotype.
 
  What will be an ideal response?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

rleezy04

  • Sr. Member
  • ****
  • Posts: 322
Reply #1 on: Jun 25, 2018
Answer to Question 1

Correct Answer: B

Answer to Question 2

Answer: The WHO Classification defines two subgroups of precursor ALL/LBL: Precursor B-cell and precursor T-cell neoplasms (leukemia/lymphoma)

B-cell ALL/LBLs are further subgrouped as ALL with recurrent cytogenetic abnormalities and ALL not otherwise specified (NOS).
Precursor B-cell molecular ID
 1212 t(12;21)(p13;q22.3)/ETV6-RUNX1 1212 t(4;11)(q21;q23)/MLL-AFF1
 1212 t(9;22)(q34;q11)/BCR-ABL1
 1212 t(5;14)(q31;q32.3)/IL3-IGH2
 1212 t(1;19)(q23.3;p13.3)/E2A-PBX1(TCF3-PBX1)
Precursor B-cell immunophenotype: CD19, CD20, CD22, CD79a
Precursor T-cell immunophenotype: TCR, CD3, CD5, CD7 (CD2, CD4, CD8)


fagboi

  • Member
  • Posts: 535
Reply 2 on: Jun 25, 2018
Great answer, keep it coming :)

peter

  • Member
  • Posts: 330
Reply 3 on: Yesterday
:D TYSM

« previous next »
 

Did you know?

The liver is the only organ that has the ability to regenerate itself after certain types of damage. As much as 25% of the liver can be removed, and it will still regenerate back to its original shape and size. However, the liver cannot regenerate after severe damage caused by alcohol.

Did you know?

The top 10 most important tips that will help you grow old gracefully include (1) quit smoking, (2) keep your weight down, (3) take supplements, (4) skip a meal each day or fast 1 day per week, (5) get a pet, (6) get medical help for chronic pain, (7) walk regularly, (8) reduce arguments, (9) put live plants in your living space, and (10) do some weight training.

Did you know?

Famous people who died from poisoning or drug overdose include, Adolf Hitler, Socrates, Juan Ponce de Leon, Marilyn Monroe, Judy Garland, and John Belushi.

Did you know?

Common abbreviations that cause medication errors include U (unit), mg (milligram), QD (every day), SC (subcutaneous), TIW (three times per week), D/C (discharge or discontinue), HS (at bedtime or "hours of sleep"), cc (cubic centimeters), and AU (each ear).

Did you know?

If you use artificial sweeteners, such as cyclamates, your eyes may be more sensitive to light. Other factors that will make your eyes more sensitive to light include use of antibiotics, oral contraceptives, hypertension medications, diuretics, and antidiabetic medications.

Because the leg muscles of children with muscular dystrophy are weak, they must perform the Gowers’ Because the leg muscles of children with muscular dystrophy are weak, they must perform the Gowers’
High rates of rural poverty have been a part of the United States from its origin to the present. ... High rates of rural poverty have been a part of the United States from its origin to the present. ...
Bulk flow by positive pressure (pressure Bulk flow by positive pressure (pressure
The Nutritional Needs of School-Aged Children Can Be Guided by MyPlate The Nutritional Needs of School-Aged Children Can Be Guided by MyPlate
Cognitive Development of Children (3 of 4) Cognitive Development of Children (3 of 4)
Response of corn selected for high and low oil content over 76 generations Response of corn selected for high and low oil content over 76 generations
Video: Biological organic compounds

For a complete list of videos, visit our video library