This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Which of the following is a positive predictive factor in children with precursor B-ALL? a. High ... (Read 41 times)

fagboi

  • Hero Member
  • *****
  • Posts: 535
on: Jun 25, 2018
Which of the following is a positive predictive factor in children with precursor B-ALL?
 
  a. High leukocyte count; less than 1 year of age
  b. Low leukocyte count; 4-10 years of age
  c. High leukocyte count; PBX1/E2A translocation
  d. Hyperdiploid chromosomes, high leukocyte count, less than 1 year of age

Question 2

Name the classifications of ALL, and explain how they differ in molecular analysis and immunophenotype.
 
  What will be an ideal response?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

rleezy04

  • Sr. Member
  • ****
  • Posts: 322
Reply #1 on: Jun 25, 2018
Answer to Question 1

Correct Answer: B

Answer to Question 2

Answer: The WHO Classification defines two subgroups of precursor ALL/LBL: Precursor B-cell and precursor T-cell neoplasms (leukemia/lymphoma)

B-cell ALL/LBLs are further subgrouped as ALL with recurrent cytogenetic abnormalities and ALL not otherwise specified (NOS).
Precursor B-cell molecular ID
 1212 t(12;21)(p13;q22.3)/ETV6-RUNX1 1212 t(4;11)(q21;q23)/MLL-AFF1
 1212 t(9;22)(q34;q11)/BCR-ABL1
 1212 t(5;14)(q31;q32.3)/IL3-IGH2
 1212 t(1;19)(q23.3;p13.3)/E2A-PBX1(TCF3-PBX1)
Precursor B-cell immunophenotype: CD19, CD20, CD22, CD79a
Precursor T-cell immunophenotype: TCR, CD3, CD5, CD7 (CD2, CD4, CD8)


fagboi

  • Member
  • Posts: 535
Reply 2 on: Jun 25, 2018
Great answer, keep it coming :)

coreycathey

  • Member
  • Posts: 333
Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

« previous next »
 

Did you know?

Signs and symptoms of a drug overdose include losing consciousness, fever or sweating, breathing problems, abnormal pulse, and changes in skin color.

Did you know?

There are more sensory neurons in the tongue than in any other part of the body.

Did you know?

Illness; diuretics; laxative abuse; hot weather; exercise; sweating; caffeine; alcoholic beverages; starvation diets; inadequate carbohydrate consumption; and diets high in protein, salt, or fiber can cause people to become dehydrated.

Did you know?

It is important to read food labels and choose foods with low cholesterol and saturated trans fat. You should limit saturated fat to no higher than 6% of daily calories.

Did you know?

The most dangerous mercury compound, dimethyl mercury, is so toxic that even a few microliters spilled on the skin can cause death. Mercury has been shown to accumulate in higher amounts in the following types of fish than other types: swordfish, shark, mackerel, tilefish, crab, and tuna.

The epidermal growth factor (EGF) pathway that promotes cell division The epidermal growth factor (EGF) pathway that promotes cell division
Why the Poor Need Children Why the Poor Need Children
A typical module-controlled high-side driver (HSD) where the module itself supplies the electrical ... A typical module-controlled high-side driver (HSD) where the module itself supplies the electrical ...
Flow data for a healthy donor (top panel) and a HIV positive patient. CD3 is a T-cell marker, CD4 is ... Flow data for a healthy donor (top panel) and a HIV positive patient. CD3 is a T-cell marker, CD4 is ...
Gender Representation in Children’s Film Gender Representation in Children’s Film
Ramey's study, children from poverty-level families IQ experiment Ramey's study, children from poverty-level families IQ experiment
Video: Types of Burns

For a complete list of videos, visit our video library