This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: What is the role of sex hormone binding globulin? How does SHBG play a role in PCOS? What will be ... (Read 80 times)

jasdeep_brar

  • Hero Member
  • *****
  • Posts: 569
on: Jun 27, 2018
What is the role of sex hormone binding globulin? How does SHBG play a role in PCOS?
 
  What will be an ideal response?

Question 2

What is meant by unopposed estrogen?
 
  What will be an ideal response?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

trog

  • Sr. Member
  • ****
  • Posts: 343
Reply #1 on: Jun 27, 2018
Answer to Question 1

Sex hormone binding globulin binds to estradiol and testosterone in the blood, allowing only a small amount to circulate as free molecules (unbound). Unbound hormones are biologically active; hormones bound to SHBG are not active. The bioavailability (activity) of estradiol and testosterone are influenced by the levels of SHBG. PCOS is primarily a syndrome of increased testosterone activity in females. Decreased levels of SHBG cause free testosterone levels to be higher and thus more bioactive, resulting in virilization in females.

Answer to Question 2

Progesterone balances the effects of estrogen. Unopposed estrogen is an excess of estrogen that is not balanced or kept in check by progesterone.


jasdeep_brar

  • Member
  • Posts: 569
Reply 2 on: Jun 27, 2018
:D TYSM

milbourne11

  • Member
  • Posts: 322
Reply 3 on: Yesterday
Gracias!

« previous next »
 

Did you know?

Alzheimer's disease affects only about 10% of people older than 65 years of age. Most forms of decreased mental function and dementia are caused by disuse (letting the mind get lazy).

Did you know?

The effects of organophosphate poisoning are referred to by using the abbreviations “SLUD” or “SLUDGE,” It stands for: salivation, lacrimation, urination, defecation, GI upset, and emesis.

Did you know?

Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.

Did you know?

The U.S. Pharmacopeia Medication Errors Reporting Program states that approximately 50% of all medication errors involve insulin.

Did you know?

Oxytocin is recommended only for pregnancies that have a medical reason for inducing labor (such as eclampsia) and is not recommended for elective procedures or for making the birthing process more convenient.

Graphical representations of ligand binding Graphical representations of ligand binding
Role-Play Scenarios Role-Play Scenarios
Role-Playing a Situation in Which a Patient Is Frightened, Angry, or Anxious Role-Playing a Situation in Which a Patient Is Frightened, Angry, or Anxious
The Role of Gases in the Atmosphere The Role of Gases in the Atmosphere
Antigen (dark green and orange) and antibody (blue and green) binding forming a complex. Antigen (dark green and orange) and antibody (blue and green) binding forming a complex.
Hormone Activity Hormone Activity
Video: Interview with Person who has Schizophrenia

For a complete list of videos, visit our video library