In interstitial lung disease, which of the following mechanisms ...

[stevenposner]

In interstitial lung disease, which of the following mechanisms contributes to impaired gas ex-change?
 
  1. Depression of respiratory drive
  2. Diffusion defect
  3. Shunt
  4. Ventilation/perfusion mismatch
  a. 1 and 4 only
  b. 2 and 3 only
  c. 2, 3, and 4 only
  d. 1, 2, and 4

Question 2

What medical problems are suggested by Mr. Jones' medical history?
 
  a. Chronic bronchitis
  b. Emphysema
  c. Occupational asthma
  d. Obstructive bronchiectasis

[janeli]

Answer to Question 1

ANS: C
Gas exchange is impaired owing to ventilation/perfusion mismatching, shunt, and decreased dif-fusion across the abnormal interstitium.

Answer to Question 2

ANS: A
Mr. Jones' medical history suggests chronic bronchitis exacerbated by a respiratory infection such as acute bronchitis, flu, or pneumonia. Chronic bronchitis is defined in clinical terms as a condi-tion in which chronic productive cough is present for at least 3 months per year for at least 2 consecutive years.