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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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In women, pharmacodynamic differences include increased sensitivity to (and increased effectiveness of) beta-blockers, opioids, selective serotonin reuptake inhibitors, and typical antipsychotics.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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On average, the stomach produces 2 L of hydrochloric acid per day.