Author Question: At a dose of 10 mg, drug X lowers total cholesterol by 50 mg/dL, while a maximum drop in cholesterol ... (Read 85 times)

BRWH · **on:** Jul 23, 2018

At a dose of 10 mg, drug X lowers total cholesterol by 50 mg/dL, while a maximum drop in cholesterol of 65mg/dL is achieved at 40 mg.

At a dose of 5 mg, drug Y lowers cholesterol by 50 mg/dL, while a maximum drop in cholesterol of 55 mg/dL is achieved at 10 mg. What can be concluded about the efficacy and potency of these two drugs?
1. Drug X is more potent, and drug Y has a higher efficacy.
2. Drug X is more potent, and has higher efficacy.
3. Drug Y is more potent, and has higher efficacy.
4. Drug Y is more potent, and drug X has a higher efficacy.

Question 2

Graded dose-response curves are most useful for determining

1. response intensity within an individual.
2. response intensity within a large group of people with different characteristics.
3. response intensity within a large group of people with similar characteristics.
4. response intensity within a small group of people with similar characteristics.

hollysheppard095 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 4
Rationale: Drug Y causes a greater drop in cholesterol at lower doses (higher potency), whereas drug X causes the highest drop in total cholesterol (efficacy).

Answer to Question 2

Correct Answer: 1
Rationale: Graded dose-response curves are used to determine response intensity within an individual.