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Author Question: At a dose of 10 mg, drug X lowers total cholesterol by 50 mg/dL, while a maximum drop in cholesterol ... (Read 111 times)

BRWH

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At a dose of 10 mg, drug X lowers total cholesterol by 50 mg/dL, while a maximum drop in cholesterol of 65mg/dL is achieved at 40 mg.
 
  At a dose of 5 mg, drug Y lowers cholesterol by 50 mg/dL, while a maximum drop in cholesterol of 55 mg/dL is achieved at 10 mg. What can be concluded about the efficacy and potency of these two drugs?
  1. Drug X is more potent, and drug Y has a higher efficacy.
  2. Drug X is more potent, and has higher efficacy.
  3. Drug Y is more potent, and has higher efficacy.
  4. Drug Y is more potent, and drug X has a higher efficacy.

Question 2

Graded dose-response curves are most useful for determining
 
  1. response intensity within an individual.
  2. response intensity within a large group of people with different characteristics.
  3. response intensity within a large group of people with similar characteristics.
  4. response intensity within a small group of people with similar characteristics.



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hollysheppard095

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Answer to Question 1

Correct Answer: 4
Rationale: Drug Y causes a greater drop in cholesterol at lower doses (higher potency), whereas drug X causes the highest drop in total cholesterol (efficacy).

Answer to Question 2

Correct Answer: 1
Rationale: Graded dose-response curves are used to determine response intensity within an individual.




BRWH

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Reply 2 on: Jul 23, 2018
Thanks for the timely response, appreciate it


cpetit11

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Reply 3 on: Yesterday
Great answer, keep it coming :)

 

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