Author Question: The nurse recognizes that which physiological change during pregnancy can alter absorption of ... (Read 23 times)

littleanan · **on:** Jul 23, 2018

The nurse recognizes that which physiological change during pregnancy can alter absorption of medication?

1. Decreased levels of progesterone cause a decrease in gastric tone and intestinal motility.
2. High estrogen levels cause decreased hydrochloric acid production, which may affect the absorption of certain acid labile drugs.
3. An enlarging uterus presses against the stomach, resulting in increased gastric emptying.
4. Increased levels of progesterone increase pulmonary blood flow, resulting in higher serum levels for respiratory drugs.

Question 2

A client admitted to the emergency department for vaginal bleeding is surprised to find she is in the third trimester of pregnancy.

An ultrasound determines the fetus is not viable. The nurse recognizes that which drug could be responsible for the fetal demise?
1. Selective serotonin reuptake inhibitors (SSRIs)
2. Fluoroquinolone
3. Acetaminophen
4. Nonsteroidal anti-inflammatory drugs (NSAIDs)
5. Angio-converting enzyme inhibitor (ACE inhibitor)

joechoochoy · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 4
Rationale 1: Increased levels of progesterone cause a decrease in gastric tone and intestinal motility.
Rationale 2: High estrogen levels cause increased hydrochloric acid production, which may affect the absorption of certain acid labile drugs.
Rationale 3: An enlarging uterus presses against the stomach, resulting in decreased gastric emptying.
Rationale 4: Increased levels of progesterone increase pulmonary blood flow, resulting in higher serum levels for respiratory drugs.
Global Rationale: Increased levels of progesterone increase pulmonary blood flow, resulting in higher serum levels for respiratory drugs. Increased levels of progesterone, not decreased, cause a decrease in gastric tone and intestinal motility. High estrogen levels cause increased hydrochloric acid production, which may affect the absorption of certain acid labile drugs. An enlarging uterus presses against the stomach, resulting in decreased gastric emptying.

Answer to Question 2

Correct Answer: 4,5
Rationale 1: SSRI drugs are category C and do not cause fetal demise.
Rationale 2: Fluoroquinolone is category C and does not cause fetal demise.
Rationale 3: Acetaminophen is category B and does not cause fetal demise.
Rationale 4: Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause fetal demise in the third trimester.
Rationale 5: ACE inhibitors are category D and can cause fetal demise.
Global Rationale: Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause fetal demise in the third trimester. ACE inhibitors are category D and can cause fetal demise. SSRI drugs and fluoroquinolones are category C and do not cause fetal demise. Acetaminophen is category B and does not cause fetal demise.