A child with severe hemophilia A receives factor VIII. The nurse ...

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A child with severe hemophilia A receives factor VIII. The nurse expects this drug to be given:
 
  a. on demand when bleeding occurs.
  b. on demand when plasma factor VIII activity is less than 1 above normal.
  c. prophylactically once weekly to maintain normal factor VIII activity.
  d. prophylactically three times weekly to maintain factor VIII activity above 1 of normal.

Question 2

A nurse is caring for a patient with HIV/acquired immunodeficiency syndrome (AIDS) who has taken protease inhibitors for 18 months. The patient has been diagnosed with active tuberculosis.
 
  Which drug(s) would the nurse expect to be added to the treatment plan of a patient with HIV/AIDS? (Select all that apply.) a. Isoniazid
  b. Rifampin Rifadin
  c. Pyrazinamide PZA
  d. Ethambutol Myambutol
  e. Rifabutin Mycobutin

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Answer to Question 1

D
Children with severe hemophilia are primary candidates for prophylactic therapy with factor VIII, and this is given every other day or three times weekly with a goal of maintaining factor VIII activity above 1 of normal. On-demand therapy is indicated when patients are bleeding or are about to undergo surgery.

Answer to Question 2

A, C, D, E
Isoniazid, pyrazinamide, ethambutol, and rifabutin could be included in the treatment of a patient with HIV/AIDS. Rifampin is contraindicated as part of the new antituberculosis regimen, because it would reduce the effects of the protease inhibitors.

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