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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
By definition, when a medication is administered intravenously, its bioavailability is 100%.
Drying your hands with a paper towel will reduce the bacterial count on your hands by 45–60%.
About 100 new prescription or over-the-counter drugs come into the U.S. market every year.
In 2006, a generic antinausea drug named ondansetron was approved. It is used to stop nausea and vomiting associated with surgery, chemotherapy, and radiation therapy.