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In the ancient and medieval periods, dysentery killed about ? of all babies before they reach 12 months of age. The disease was transferred through contaminated drinking water, because there was no way to adequately dispose of sewage, which contaminated the water.
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In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.