« previous next »

Author Question: Describe the role of dopamine in reinforcing brain stimulation. What will be an ideal ... (Read 65 times)

iveyjurea

  • Hero Member
  • *****
  • Posts: 555
on: Jun 22, 2018
Describe the role of dopamine in reinforcing brain stimulation.
 
  What will be an ideal response?

Question 2

Discuss the role of the NMDA receptor in LTP.
 
  What will be an ideal response?


janieazgirl

  • Sr. Member
  • ****
  • Posts: 300
Reply #1 on: Jun 22, 2018
Answer to Question 1

Answer: The ventral tegmental area (VTA) projects to the nucleus accumbens (NAcc) via the mesolimbic dopamine pathway. Increases of dopamine within the NAcc are reinforcing. Natural reinforcers (food for a hungry rat) will elicit this increase in DA, as will drugs of abuse such as amphetamine that are also reinforcing (i.e., rats will make a response that delivers the drug into their blood stream or directly into the NAcc).

Answer to Question 2

Answer: NMDA receptors are found in the hippocampus, are activated by glutamate and depolarization, and control a calcium channel in the postsynaptic dendrite. Blockade of NMDA receptors, using AP5, blocks the formation of LTP.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
« previous next »
 

Did you know?

Excessive alcohol use costs the country approximately $235 billion every year.

Did you know?

Today, nearly 8 out of 10 pregnant women living with HIV (about 1.1 million), receive antiretrovirals.

Did you know?

There are approximately 3 million unintended pregnancies in the United States each year.

Did you know?

In 2010, opiate painkllers, such as morphine, OxyContin®, and Vicodin®, were tied to almost 60% of drug overdose deaths.

Did you know?

The cure for trichomoniasis is easy as long as the patient does not drink alcoholic beverages for 24 hours. Just a single dose of medication is needed to rid the body of the disease. However, without proper precautions, an individual may contract the disease repeatedly. In fact, most people develop trichomoniasis again within three months of their last treatment.

Brain Brain
Human Brain Human Brain
Key anatomical features of Homo habilis include reduced facial size, a parabolic palate, and some br Key anatomical features of Homo habilis include reduced facial size, a parabolic palate, and some br
Two regions of the brain involved in sleep. The anterior hypothalamus and adjacent basal forebrain ... Two regions of the brain involved in sleep. The anterior hypothalamus and adjacent basal forebrain ...
Scanning the Brain Scanning the Brain
How body makes blood flow more into brain instead of foot? How body makes blood flow more into brain instead of foot?
Video: Mycobacterium tuberculosis: Drug Resistance and Natural Selection

For a complete list of videos, visit our video library