« previous next »

Author Question: Describe the role of dopamine in reinforcing brain stimulation. What will be an ideal ... (Read 59 times)

iveyjurea

  • Hero Member
  • *****
  • Posts: 555
on: Jun 22, 2018
Describe the role of dopamine in reinforcing brain stimulation.
 
  What will be an ideal response?

Question 2

Discuss the role of the NMDA receptor in LTP.
 
  What will be an ideal response?


janieazgirl

  • Sr. Member
  • ****
  • Posts: 300
Reply #1 on: Jun 22, 2018
Answer to Question 1

Answer: The ventral tegmental area (VTA) projects to the nucleus accumbens (NAcc) via the mesolimbic dopamine pathway. Increases of dopamine within the NAcc are reinforcing. Natural reinforcers (food for a hungry rat) will elicit this increase in DA, as will drugs of abuse such as amphetamine that are also reinforcing (i.e., rats will make a response that delivers the drug into their blood stream or directly into the NAcc).

Answer to Question 2

Answer: NMDA receptors are found in the hippocampus, are activated by glutamate and depolarization, and control a calcium channel in the postsynaptic dendrite. Blockade of NMDA receptors, using AP5, blocks the formation of LTP.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
« previous next »
 

Did you know?

On average, someone in the United States has a stroke about every 40 seconds. This is about 795,000 people per year.

Did you know?

Signs and symptoms that may signify an eye tumor include general blurred vision, bulging eye(s), double vision, a sensation of a foreign body in the eye(s), iris defects, limited ability to move the eyelid(s), limited ability to move the eye(s), pain or discomfort in or around the eyes or eyelids, red or pink eyes, white or cloud spots on the eye(s), colored spots on the eyelid(s), swelling around the eyes, swollen eyelid(s), and general vision loss.

Did you know?

The oldest recorded age was 122. Madame Jeanne Calment was born in France in 1875 and died in 1997. She was a vegetarian and loved olive oil, port wine, and chocolate.

Did you know?

Vital signs (blood pressure, temperature, pulse rate, respiration rate) should be taken before any drug administration. Patients should be informed not to use tobacco or caffeine at least 30 minutes before their appointment.

Did you know?

The U.S. Preventive Services Task Force recommends that all women age 65 years of age or older should be screened with bone densitometry.

Brain mass as a function of body mass in mammals. Brain mass as a function of body mass in mammals.
brain model brain model
Human Brain Human Brain
A Midsagittal View of the Brain and Part of the Spinal Cord A Midsagittal View of the Brain and Part of the Spinal Cord
brain stimulation brain stimulation
Brain Hemisphere Activity Brain Hemisphere Activity
Video: Magnetic resonance imaging (MRI)

For a complete list of videos, visit our video library