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Author Question: A researcher is annotating a newly-sequenced chromosome that they constructed from contigs sequenced ... (Read 132 times)

roselinechinyere27m

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A researcher is annotating a newly-sequenced chromosome that they constructed from contigs sequenced from a sample of Antarctic ice.  The cell/organism that the chromosome came from is not known, however it yielded a single circular chromosome.  You are asked to run a BLAST search to help this researcher identify the most related organism in GenBank.  What would be the best strategy?
◦ Compare the most unusual portion of this newly-discovered chromosome to al known animal genomes.
◦ Perform many careful one-by-one comparisons between the newly-discovered DNA sequence and species selected from GenBank, one at a time.
◦ Use several ~1000bp portions of the DNA sequence to search for the closest matches from among the entire available database.
◦ Look for a nearly identical match to a very small part (20-40 bp) of the chromosome from all known ice bacteria.
◦ Look for an exact match to the whole chromosome.


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Marked as best answer by roselinechinyere27m on Jan 12, 2022

orangecrush

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roselinechinyere27m

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Reply 2 on: Jan 12, 2022
Wow, this really help


billybob123

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Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

 

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