This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: An increase in the concentration of 2,3-BPG: a. Puts hemoglobin the relaxed conformation form ... (Read 120 times)

luvbio

  • Hero Member
  • *****
  • Posts: 623
on: Jun 25, 2018
An increase in the concentration of 2,3-BPG:
 
  a. Puts hemoglobin the relaxed conformation form
  b. Shifts the oxygen dissociation curve to the left
  c. Increases the affinity of hemoglobin for oxygen
  d. Is present in patients with severe anemia and decreased blood pH (acidosis)

Question 2

Why is it important that synthesis of globin chains and heme be balanced in the RBCs?
 
  a. Excess concentration of protoporphyrin increases bilirubin in plasma.
  b. An excess of one of the components of hemoglobin decreases RBC survival.
  c. An excess of one of the components of hemoglobin increases RBC survival leading to an eventual elevated RBC count.
  d. An excess of globin chains significantly decreases the concentration of globin chain messenger ribonucleic acid (mRNA) in the developing RBCs.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

braelync

  • Sr. Member
  • ****
  • Posts: 350
Reply #1 on: Jun 25, 2018
Answer to Question 1

ANS: D
Patients who are severely anemic and those with a decreased blood pH, among others, have increased levels of 2,3-BPG. This shifts the oxygen dissociation curve to the right, thus deceasing the affinity of hemoglobin for oxygen. The result is more effective delivery of oxygen to tissue. An elevated concentration places the hemoglobin molecule in the tense conformational form.

Answer to Question 2

ANS: B
An excess of one of the components of hemoglobin can decrease RBC survival in circulation. None of the other listed items are true in the presence of an excess.


luvbio

  • Member
  • Posts: 623
Reply 2 on: Jun 25, 2018
Excellent

raili21

  • Member
  • Posts: 324
Reply 3 on: Yesterday
Gracias!

« previous next »
 

Did you know?

The liver is the only organ that has the ability to regenerate itself after certain types of damage. As much as 25% of the liver can be removed, and it will still regenerate back to its original shape and size. However, the liver cannot regenerate after severe damage caused by alcohol.

Did you know?

Sperm cells are so tiny that 400 to 500 million (400,000,000–500,000,000) of them fit onto 1 tsp.

Did you know?

Approximately 15–25% of recognized pregnancies end in miscarriage. However, many miscarriages often occur before a woman even knows she is pregnant.

Did you know?

After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.

Did you know?

According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.

Arctic and alpine cushion plant form and orientation increases heat gain from sunlight and the surro Arctic and alpine cushion plant form and orientation increases heat gain from sunlight and the surro
Effect of substrate concentration on the initial velocity of an enzyme-catalyzed reaction Effect of substrate concentration on the initial velocity of an enzyme-catalyzed reaction
Atmospheric pressure decreases with increase in altitude. Atmospheric pressure decreases with increase in altitude.
Effect of an Increase in Technological Progress Effect of an Increase in Technological Progress
The dissociation equilibrium constants for the protonated form of alanine (a diprotic amino ... The dissociation equilibrium constants for the protonated form of alanine (a diprotic amino ...
Structure of hemoglobin, the oxygen-transporting protein of red blood cells. It consists of four glo Structure of hemoglobin, the oxygen-transporting protein of red blood cells. It consists of four glo
Video: Introduction to Heart Attacks

For a complete list of videos, visit our video library