This topic contains a solution. Click here to go to the answer

Author Question: CD34 enumeration is useful in bone marrow and peripheral blood stem cell transplantation. For this ... (Read 52 times)

ts19998

  • Hero Member
  • *****
  • Posts: 531
CD34 enumeration is useful in bone marrow and peripheral blood stem cell transplantation. For this enumeration, the EWGCCA recommendations include proper technique and interpretation of the flow cytometry analysis.
 
  Which of the following standards was recommended for proper acquisition of events?
 
  a. Include platelets and unlysed red blood cells and debris
  b. Include only CD34 dim staining populations
  c. Use bright fluorochrome conjugates of class II or III monoclonal antibodies that detect all glycoforms of CD34
  d. Acquire only 10 CD34 positive cells

Question 2

Name at least two pitfalls in immunophenotyping mature lymphoid malignancies, and explain how you would correct this.
 
  What will be an ideal response?



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

jamesnevil303

  • Sr. Member
  • ****
  • Posts: 337
Answer to Question 1

Correct Answer: C

Answer to Question 2

Answer: Some malignant B- cell lymphoproliferative disorders lack surface immunoglobulin and can be overlooked. Some lack surface antigens or an abnormal phenotype. Hodgkin lymphoma not only lacks many lymphoid cell antigens but also the neoplastic cells are rare, and a single cell suspension could be difficult to prepare because of fibrosis. Some abnormal phenotypes are not specific for a particular lymphoid neoplasm. It is important to use morphology together with immunophenotyping to help overcome these pitfalls.




ts19998

  • Member
  • Posts: 531
Reply 2 on: Jun 25, 2018
Gracias!


skipfourms123

  • Member
  • Posts: 343
Reply 3 on: Yesterday
YES! Correct, THANKS for helping me on my review

 

Did you know?

Tobacco depletes the body of vitamins A, C, and E, which can result in any of the following: dry hair, dry skin, dry eyes, poor growth, night blindness, abscesses, insomnia, fatigue, reproductive system problems, sinusitis, pneumonia, frequent respiratory problems, skin disorders, weight loss, rickets, osteomalacia, nervousness, muscle spasms, leg cramps, extremity numbness, bone malformations, decayed teeth, difficulty in walking, irritability, restlessness, profuse sweating, increased uric acid (gout), joint damage, damaged red blood cells, destruction of nerves, infertility, miscarriage, and many types of cancer.

Did you know?

The average person is easily confused by the terms pharmaceutics and pharmacology, thinking they are one and the same. Whereas pharmaceutics is the science of preparing and dispensing drugs (otherwise known as the science of pharmacy), pharmacology is the study of medications.

Did you know?

According to the National Institute of Environmental Health Sciences, lung disease is the third leading killer in the United States, responsible for one in seven deaths. It is the leading cause of death among infants under the age of one year.

Did you know?

There used to be a metric calendar, as well as metric clocks. The metric calendar, or "French Republican Calendar" divided the year into 12 months, but each month was divided into three 10-day weeks. Each day had 10 decimal hours. Each hour had 100 decimal minutes. Due to lack of popularity, the metric clocks and calendars were ended in 1795, three years after they had been first marketed.

Did you know?

About 3% of all pregnant women will give birth to twins, which is an increase in rate of nearly 60% since the early 1980s.

For a complete list of videos, visit our video library