Answer to Question 1
There are only two progenitor cells that eventually produce all white cell types: a myeloid stem cell and a lymphoid stem cell. Mutations resulting in leukemia occur within the genes that drive the differentiation or maturation of these two cell lines.
Answer to Question 2
Functional immunoincompetence results from a proliferation of immature or defective cells (incompetent cells) that are not capable of carrying out their normal function. Often, a proliferation of immunoincompetent cells is accompanied by a decreased number of normal, competent cells. The decreased number of normal cells results when the over-proliferation of one cell type outcompetes normal cells for resources (space and nutrients) in the bone marrow.
Acute lymphocytic leukemia.
Major Diagnostic Categories of Mental Disorders
Major Diagnostic Categories of Mental Disorders Cont
Summary of Hale’s Lactation Risk Categories
Major Categories of Diseases
Functional categories of human genes