Answer to Question 1
There are only two progenitor cells that eventually produce all white cell types: a myeloid stem cell and a lymphoid stem cell. Mutations resulting in leukemia occur within the genes that drive the differentiation or maturation of these two cell lines.
Answer to Question 2
Functional immunoincompetence results from a proliferation of immature or defective cells (incompetent cells) that are not capable of carrying out their normal function. Often, a proliferation of immunoincompetent cells is accompanied by a decreased number of normal, competent cells. The decreased number of normal cells results when the over-proliferation of one cell type outcompetes normal cells for resources (space and nutrients) in the bone marrow.
Acute lymphocytic leukemia.
Smith and Snell’s Five Religious Categories
Table 6.1 illustrates the main regime types and their differences. It breaks the regimes into four
(a) Acute myelocytic leukemia: The tumor cells are of myeloid rather than lymphoid lineage. (b) ...
Food and Drug Administration (FDA) Pregnancy Categories
An overview of the various categories of repetitive DNA