Using layman's terms, describe the action of mast cell ...

[jc611]

Using layman's terms, describe the action of mast cell stabilizing drugs that modulate mast cell response and eosinophil recruitment and how these drugs contribute to the treatment of asthma.
 
  What will be an ideal response?

Question 2

What does reversible airway disease mean? Why is asthma considered a reversible airway disease?
 
  What will be an ideal response?

[leahchrapun]

Answer to Question 1

Mast cells are a type of white cell capable of releasing a large amount of histamine, which sets off a cascade of reactions that in some people result in constriction of the airways (commonly called an asthma attack). Eosinophils, also a type of white cell, are drawn (recruited) to the site of an allergic reaction and they too release histamine and other immune system chemicals that result in an inappropriate (exaggerated) immune response. Mast cell stabilizers prevent the mast cell from releasing histamine and interfere with the process that draws eosinophils to the site of the reaction. These actions lessen the release of histamine, thereby lessening the overall immune response and decreasing the incidence of asthma.

Answer to Question 2

Reversible airway disease refers to a disease that causes intermittent constriction of the airways. The constriction is episodic, not constant. Asthma is a reversible airway disease because the airways only constrict during an asthma attack. Once the attack is over, the airway diameter returns to normal.