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The use of salicylates dates back 2,500 years to Hippocrates’s recommendation of willow bark (from which a salicylate is derived) as an aid to the pains of childbirth. However, overdosage of salicylates can harm body fluids, electrolytes, the CNS, the GI tract, the ears, the lungs, the blood, the liver, and the kidneys and cause coma or death.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
Drying your hands with a paper towel will reduce the bacterial count on your hands by 45–60%.
If you could remove all of your skin, it would weigh up to 5 pounds.
Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.