Author Question: Phenelzine (Nardil) has been discontinued as a drug order for a patient. How much time must be ... (Read 60 times)

Garrulous · **on:** Jul 23, 2018

Phenelzine (Nardil) has been discontinued as a drug order for a patient. How much time must be observed before the patient can start a new drug?

a. 2 days
b. 5 days
c. 1 week
d. 2 weeks

Question 2

The patient has been started on a treatment regimen which includes the use of lithium. As part of the teaching plan regarding lithium, the patient should be instructed that he should avoid:

a. Becoming sleep-deprived
b. Failing to exercise daily
c. Failing to stay on his prescribed dietary regimen
d. Becoming dehydrated

jesse.fleming · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: D
Phenelzine is a monoamine oxidase inhibitor (MAOI) that produces irreversible inhibition of monoamine oxidase. It takes about 2 weeks for sufficient synthesis of new enzyme to occur. Thus the start of a new drug must be delayed for 2 weeks after discontinuing phenelzine.

Answer to Question 2

ANS: D
The most common cause of lithium accumulation in patients adhering to the treatment regimen is sodium depletion and dehydration, which reduces the volume of distribution of lithium and in-creases serum levels.