Phenelzine (Nardil) has been discontinued as a drug order for a ...

[Garrulous]

Phenelzine (Nardil) has been discontinued as a drug order for a patient. How much time must be observed before the patient can start a new drug?
 
  a. 2 days
  b. 5 days
  c. 1 week
  d. 2 weeks

Question 2

The patient has been started on a treatment regimen which includes the use of lithium. As part of the teaching plan regarding lithium, the patient should be instructed that he should avoid:
 
  a. Becoming sleep-deprived
  b. Failing to exercise daily
  c. Failing to stay on his prescribed dietary regimen
  d. Becoming dehydrated

[jesse.fleming]

Answer to Question 1

ANS: D
Phenelzine is a monoamine oxidase inhibitor (MAOI) that produces irreversible inhibition of monoamine oxidase. It takes about 2 weeks for sufficient synthesis of new enzyme to occur. Thus the start of a new drug must be delayed for 2 weeks after discontinuing phenelzine.

Answer to Question 2

ANS: D
The most common cause of lithium accumulation in patients adhering to the treatment regimen is sodium depletion and dehydration, which reduces the volume of distribution of lithium and in-creases serum levels.

[Garrulous]

Thanks for the timely response, appreciate it

[Animal_Goddess]

Gracias!