This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A patient is receiving fluorouracil (Adrucil) as a continuous intravenous dose to treat a solid ... (Read 76 times)

misspop

  • Hero Member
  • *****
  • Posts: 540
on: Jul 23, 2018
A patient is receiving fluorouracil (Adrucil) as a continuous intravenous dose to treat a solid tumor. The patient reports soreness and blisters in the mouth, loose stools, and tingling of the hands and feet. What will the nurse do?
 
  a. Contact the provider to discuss bolus dosing instead of continuous dosing.
  b. Discontinue the medication and contact the provider to report these symptoms.
  c. Reassure the patient that these are expected, uncomfortable side effects.
  d. Request an order for dexamethasone to treat these side effects.

Question 2

A nurse is teaching a patient who will undergo chemotherapy with fluorouracil (Adrucil) to treat a solid tumor. Which statement by the patient indicates understanding of this chemotherapeutic agent's actions?
 
  a. Fluorouracil acts to deprive cancer cells of thymidylate needed to make DNA.
  b. Fluorouracil causes accumulation of adenosine, which inhibits DNA synthesis.
  c. Fluorouracil disrupts the biosynthesis of nucleic acids.
  d. Fluorouracil inhibits DNA polymerase in cancer cells.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

bob

  • Sr. Member
  • ****
  • Posts: 343
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: B
Stomatitis, GI symptoms, and palmar-plantar erythrodysesthesias are dose-limiting side effects of fluorouracil, characterized by the symptoms described. When these occur, the provider should be notified. Continuous dosing is generally less toxic than bolus dosing. Reassurance without discontinuing the medication and contacting the provider is not correct. Dexamethasone is not given to counter these effects.

Answer to Question 2

ANS: A
Fluorouracil acts by depriving cancer cells of thymidylate, which is necessary to make DNA. It does not cause the accumulation of adenosine, disrupt the biosynthesis of nucleic acids, or inhibit DNA polymerase.


misspop

  • Member
  • Posts: 540
Reply 2 on: Jul 23, 2018
Great answer, keep it coming :)

mcabuhat

  • Member
  • Posts: 344
Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

« previous next »
 

Did you know?

Signs and symptoms that may signify an eye tumor include general blurred vision, bulging eye(s), double vision, a sensation of a foreign body in the eye(s), iris defects, limited ability to move the eyelid(s), limited ability to move the eye(s), pain or discomfort in or around the eyes or eyelids, red or pink eyes, white or cloud spots on the eye(s), colored spots on the eyelid(s), swelling around the eyes, swollen eyelid(s), and general vision loss.

Did you know?

HIV testing reach is still limited. An estimated 40% of people with HIV (more than 14 million) remain undiagnosed and do not know their infection status.

Did you know?

Signs and symptoms of a drug overdose include losing consciousness, fever or sweating, breathing problems, abnormal pulse, and changes in skin color.

Did you know?

The Centers for Disease Control and Prevention has released reports detailing the deaths of infants (younger than 1 year of age) who died after being given cold and cough medications. This underscores the importance of educating parents that children younger than 2 years of age should never be given over-the-counter cold and cough medications without consulting their physicians.

Did you know?

Calcitonin is a naturally occurring hormone. In women who are at least 5 years beyond menopause, it slows bone loss and increases spinal bone density.

THE DIMENSIONS OF PATIENT-CENTERED CARE THE DIMENSIONS OF PATIENT-CENTERED CARE
Pigmented bands in nail of patient with dark skin Pigmented bands in nail of patient with dark skin
Dose-Response Curves for Morphine Dose-Response Curves for Morphine
Dialysis machine showing diffusion of concentrations, which are the same, between the patient’s ... Dialysis machine showing diffusion of concentrations, which are the same, between the patient’s ...
Drugs to Treat Alzheimer’s Disease Drugs to Treat Alzheimer’s Disease
Video: Alternative Energy Sources

For a complete list of videos, visit our video library