This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A patient is receiving fluorouracil (Adrucil) as a continuous intravenous dose to treat a solid ... (Read 78 times)

misspop

  • Hero Member
  • *****
  • Posts: 540
on: Jul 23, 2018
A patient is receiving fluorouracil (Adrucil) as a continuous intravenous dose to treat a solid tumor. The patient reports soreness and blisters in the mouth, loose stools, and tingling of the hands and feet. What will the nurse do?
 
  a. Contact the provider to discuss bolus dosing instead of continuous dosing.
  b. Discontinue the medication and contact the provider to report these symptoms.
  c. Reassure the patient that these are expected, uncomfortable side effects.
  d. Request an order for dexamethasone to treat these side effects.

Question 2

A nurse is teaching a patient who will undergo chemotherapy with fluorouracil (Adrucil) to treat a solid tumor. Which statement by the patient indicates understanding of this chemotherapeutic agent's actions?
 
  a. Fluorouracil acts to deprive cancer cells of thymidylate needed to make DNA.
  b. Fluorouracil causes accumulation of adenosine, which inhibits DNA synthesis.
  c. Fluorouracil disrupts the biosynthesis of nucleic acids.
  d. Fluorouracil inhibits DNA polymerase in cancer cells.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

bob

  • Sr. Member
  • ****
  • Posts: 343
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: B
Stomatitis, GI symptoms, and palmar-plantar erythrodysesthesias are dose-limiting side effects of fluorouracil, characterized by the symptoms described. When these occur, the provider should be notified. Continuous dosing is generally less toxic than bolus dosing. Reassurance without discontinuing the medication and contacting the provider is not correct. Dexamethasone is not given to counter these effects.

Answer to Question 2

ANS: A
Fluorouracil acts by depriving cancer cells of thymidylate, which is necessary to make DNA. It does not cause the accumulation of adenosine, disrupt the biosynthesis of nucleic acids, or inhibit DNA polymerase.


misspop

  • Member
  • Posts: 540
Reply 2 on: Jul 23, 2018
Excellent

Liamb2179

  • Member
  • Posts: 365
Reply 3 on: Yesterday
Gracias!

« previous next »
 

Did you know?

GI conditions that will keep you out of the U.S. armed services include ulcers, varices, fistulas, esophagitis, gastritis, congenital abnormalities, inflammatory bowel disease, enteritis, colitis, proctitis, duodenal diverticula, malabsorption syndromes, hepatitis, cirrhosis, cysts, abscesses, pancreatitis, polyps, certain hemorrhoids, splenomegaly, hernias, recent abdominal surgery, GI bypass or stomach stapling, and artificial GI openings.

Did you know?

More than 4.4billion prescriptions were dispensed within the United States in 2016.

Did you know?

Illicit drug use costs the United States approximately $181 billion every year.

Did you know?

Malaria mortality rates are falling. Increased malaria prevention and control measures have greatly improved these rates. Since 2000, malaria mortality rates have fallen globally by 60% among all age groups, and by 65% among children under age 5.

Did you know?

Drugs are in development that may cure asthma and hay fever once and for all. They target leukotrienes, which are known to cause tightening of the air passages in the lungs and increase mucus productions in nasal passages.

Photo of the neck of a patient with non-Hodgkin’s lymphoma showing the swelling associated with enla Photo of the neck of a patient with non-Hodgkin’s lymphoma showing the swelling associated with enla
Continuous positive airway pressure (CPAP) device. The sleeping subject is receiving the benefits of Continuous positive airway pressure (CPAP) device. The sleeping subject is receiving the benefits of
The Reticular Activating System and Related Regions in the Brain Are Important Areas of Focus for D The Reticular Activating System and Related Regions in the Brain Are Important Areas of Focus for D
Assisting the patient to transfer from the bed or examining table to a wheelchair. Assisting the patient to transfer from the bed or examining table to a wheelchair.
Cyanosis as shown here at the patient’s fingertips results from a lack of oxygen in the tissues Cyanosis as shown here at the patient’s fingertips results from a lack of oxygen in the tissues
Anatomy of the heart. Remember: It is labeled right and left based on the patient’s perspective. Anatomy of the heart. Remember: It is labeled right and left based on the patient’s perspective.
Video: Blood Pressure Measurement

For a complete list of videos, visit our video library