This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A patient is receiving fluorouracil (Adrucil) as a continuous intravenous dose to treat a solid ... (Read 41 times)

misspop

  • Hero Member
  • *****
  • Posts: 540
on: Jul 23, 2018
A patient is receiving fluorouracil (Adrucil) as a continuous intravenous dose to treat a solid tumor. The patient reports soreness and blisters in the mouth, loose stools, and tingling of the hands and feet. What will the nurse do?
 
  a. Contact the provider to discuss bolus dosing instead of continuous dosing.
  b. Discontinue the medication and contact the provider to report these symptoms.
  c. Reassure the patient that these are expected, uncomfortable side effects.
  d. Request an order for dexamethasone to treat these side effects.

Question 2

A nurse is teaching a patient who will undergo chemotherapy with fluorouracil (Adrucil) to treat a solid tumor. Which statement by the patient indicates understanding of this chemotherapeutic agent's actions?
 
  a. Fluorouracil acts to deprive cancer cells of thymidylate needed to make DNA.
  b. Fluorouracil causes accumulation of adenosine, which inhibits DNA synthesis.
  c. Fluorouracil disrupts the biosynthesis of nucleic acids.
  d. Fluorouracil inhibits DNA polymerase in cancer cells.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

bob

  • Sr. Member
  • ****
  • Posts: 343
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: B
Stomatitis, GI symptoms, and palmar-plantar erythrodysesthesias are dose-limiting side effects of fluorouracil, characterized by the symptoms described. When these occur, the provider should be notified. Continuous dosing is generally less toxic than bolus dosing. Reassurance without discontinuing the medication and contacting the provider is not correct. Dexamethasone is not given to counter these effects.

Answer to Question 2

ANS: A
Fluorouracil acts by depriving cancer cells of thymidylate, which is necessary to make DNA. It does not cause the accumulation of adenosine, disrupt the biosynthesis of nucleic acids, or inhibit DNA polymerase.


misspop

  • Member
  • Posts: 540
Reply 2 on: Jul 23, 2018
YES! Correct, THANKS for helping me on my review

epscape

  • Member
  • Posts: 335
Reply 3 on: Yesterday
:D TYSM

« previous next »
 

Did you know?

The shortest mature adult human of whom there is independent evidence was Gul Mohammed in India. In 1990, he was measured in New Delhi and stood 22.5 inches tall.

Did you know?

Symptoms of kidney problems include a loss of appetite, back pain (which may be sudden and intense), chills, abdominal pain, fluid retention, nausea, the urge to urinate, vomiting, and fever.

Did you know?

Stevens-Johnson syndrome and Toxic Epidermal Necrolysis syndrome are life-threatening reactions that can result in death. Complications include permanent blindness, dry-eye syndrome, lung damage, photophobia, asthma, chronic obstructive pulmonary disease, permanent loss of nail beds, scarring of mucous membranes, arthritis, and chronic fatigue syndrome. Many patients' pores scar shut, causing them to retain heat.

Did you know?

In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.

Did you know?

Hippocrates noted that blood separates into four differently colored liquids when removed from the body and examined: a pure red liquid mixed with white liquid material with a yellow-colored froth at the top and a black substance that settles underneath; he named these the four humors (for blood, phlegm, yellow bile, and black bile).

Urinary catheterization. The procedure involves the insertion of a flexible tube, or catheter, throu Urinary catheterization. The procedure involves the insertion of a flexible tube, or catheter, throu
A patient examination room should be simple and efficiently designed. A patient examination room should be simple and efficiently designed.
Apply direct pressure to the patient’s wound. Apply direct pressure to the patient’s wound.
A pacemaker in a patient’s chest. A pacemaker in a patient’s chest.
A general scheme for adding one amino acid in solid-phase peptide synthesis A general scheme for adding one amino acid in solid-phase peptide synthesis
Video: The life cycle of protein

For a complete list of videos, visit our video library