An older adult woman has been diagnosed with acute lymphoblastic leukemia (ALL) and her care team has identified potential benefits of imatinib.
Which of the following characteristics of this patient's current health status may preclude the use of imatinib?
A) The patient has type 2 diabetes mellitus that is controlled using diet and oral antihyperglycemics.
B) The patient has chronic heart failure resulting in significant peripheral edema.
C) The patient experienced a mild ischemic stroke several years ago and had transient ischemic attacks last year.
D) The patient had a total knee arthroplasty several months earlier.
Question 2
A nurse on an oncology unit is aware of the need to assess for adverse effects in patients who are being treated with rituximab. The risks of adverse effects are highest at what point during the course of treatment?
A) Shortly after the initiation of the first infusion of rituximab
B) After 6 to 8 weeks of treatment at the maximum dose
C) At each point that the dosage of rituximab is increased
D) 48 to 72 hours after the first dose has been administered