A patient of Asian descent has been diagnosed with hypertension. ...

[c0205847]

A patient of Asian descent has been diagnosed with hypertension. He is placed on a beta-blocker. Why is the dose lower than in most other patients?
 
  A) Asians metabolize and excrete beta-blockers slower.
  B) Asians metabolize beta-blockers in the small intestine.
  C) Asians have a diminished renal excretion of beta-blockers.
  D) Asians are more likely to have a lower albumin level.

Question 2

An intensive care unit (ICU) nurse is preparing to administer an intravenous dose of imipenemcilastatin to a patient who is being treated for sepsis. What aspect of this patient's history would contraindicate the use of this drug?
 
  A) The patient has a history of type 1 diabetes mellitus.
  B) The patient is showing signs and symptoms of fluid volume excess.
  C) The patient's most recent creatinine level was 140 mol/L (high).
  D) The patient has a documented allergy to penicillin.

[Bison]

Answer to Question 1

A
Feedback:
Asians in general need much smaller doses of beta-blockers because they metabolize and excrete beta-blockers slowly. They do not metabolize beta-blockers in the small intestine. They do not have diminished renal excretion of beta-blockers. They do not have a lower albumin level.

Answer to Question 2

D
Feedback:
It is important to avoid administering imipenemcilastatin and the other carbapenems to people with life-threatening allergic reactions to penicillin. Diabetes, slightly increased creatinine levels, and fluid overload do not necessarily contraindicate the use of imipenemcilastatin.

[c0205847]

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[Bison]

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