A patient tells the nurse, I took my sleeping pill yesterday ...

[rayancarla1]

A patient tells the nurse, I took my sleeping pill yesterday evening, but it didn't seem to work for me like it usually does. The nurse should consider which of the following variables that can affect drug absorption? Select all that apply.
 
  A) GI function
  B) Blood flow to the site of administration
  C) The presence of other drugs
  D) Route of administration
  E) The presence of receptor agonists

Question 2

A 3-year-old child is seen in the pediatric office for a dry, hacking cough. The mother is requesting a prescription for dextromethorphan.
 
  In providing patient education, which of the following provides the most effective teaching regarding the use of dextromethorphan in children? A) Dextromethorphan suppresses cough in children.
  B) Dextromethorphan is ineffective in children.
  C) Dextromethorphan must be combined with codeine.
  D) Dextromethorphan raises blood pressure in children.

[31809pancho]

Answer to Question 1

A, B, C, D
Feedback:
Numerous factors affect the rate and extent of drug absorption, including dosage form, route of administration, blood flow to the site of administration, GI function, the presence of food or other drugs, and other variables. Agonist activity is a relevant variable, but this is not an aspect of absorption.

Answer to Question 2

B
Feedback:
Although antitussives continue to be used and adults report beneficial effect in reducing cough, antitussives, particularly dextromethorphan, have not been demonstrated to be effective in children and adolescents. Adverse effects of dextromethorphan in children include behavioral disturbances and respiratory depression, not high blood pressure.

[rayancarla1]

TYSM

[jordangronback]

Excellent