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Author Question: Cruciferous vegetables may alter drug pharmacokinetics by: 1. Enhancing absorption of weakly ... (Read 28 times)

Collmarie

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on: Jul 24, 2018
Cruciferous vegetables may alter drug pharmacokinetics by:
 
  1. Enhancing absorption of weakly acidic drugs
  2. Altering CYP 3A4 activity, leading to elevated levels of drugs, such as the statins
  3. Inducing CYP 1A2, possibly leading to therapeutic failure of drugs metabolized by CYP 1A2
  4. Decreasing first-pass metabolism of drugs

Question 2

Grapefruit juice contains furanocoumarins that have been found to:
 
  1. Alter absorption of drugs through competition for binding sites
  2. Inhibit CYP 3A4, leading to decreased first-pass metabolism of drugs
  3. Alter vitamin K metabolism, leading to prolonged bleeding
  4. Enhance absorption of calcium and vitamin D


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akudia

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Reply #1 on: Jul 24, 2018
Answer to Question 1

3

Answer to Question 2

2


Collmarie

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Reply 2 on: Jul 24, 2018
Wow, this really help

okolip

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Reply 3 on: Yesterday
Great answer, keep it coming :)

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