What are currently thought to be the health benefits associated ...

[arivle123]

What are currently thought to be the health benefits associated with moderate alcohol consumption?

Question 2

Why does alcohol metabolism cause lipids to accumulate in the liver?

[ryansturges]

Answer to Question 1

 Moderate drinkers tend to live longer than nondrinkers (and those who drink heavily)
 Associated with decreased risk for:
o cardiovascular disease (dose-dependent increases in HDL-cholesterol levels; dose-dependent decreases in triglycerides; anti-inflammatory effect)
o strokes (decreases levels of fibrinogen, which promotes blood clot formation; increases levels of an enzyme that dissolves blood clots)
o gallstones
o age-related memory loss
o type 2 diabetes (increases insulin sensitivity  lowering blood glucose)

Answer to Question 2

 Decreased fatty acid breakdown (-oxidation)
 Increased uptake of fatty acids from the blood
 Increased fatty acid synthesis and triglyceride formation (lipogenesis)
 Decreased transport of triglycerides from the liver into the blood

[arivle123]

TYSM

[amit]

Gracias!