« previous next »

Author Question: Describe the role of dopamine in reinforcing brain stimulation. What will be an ideal ... (Read 48 times)

iveyjurea

  • Hero Member
  • *****
  • Posts: 555
on: Jun 22, 2018
Describe the role of dopamine in reinforcing brain stimulation.
 
  What will be an ideal response?

Question 2

Discuss the role of the NMDA receptor in LTP.
 
  What will be an ideal response?


janieazgirl

  • Sr. Member
  • ****
  • Posts: 300
Reply #1 on: Jun 22, 2018
Answer to Question 1

Answer: The ventral tegmental area (VTA) projects to the nucleus accumbens (NAcc) via the mesolimbic dopamine pathway. Increases of dopamine within the NAcc are reinforcing. Natural reinforcers (food for a hungry rat) will elicit this increase in DA, as will drugs of abuse such as amphetamine that are also reinforcing (i.e., rats will make a response that delivers the drug into their blood stream or directly into the NAcc).

Answer to Question 2

Answer: NMDA receptors are found in the hippocampus, are activated by glutamate and depolarization, and control a calcium channel in the postsynaptic dendrite. Blockade of NMDA receptors, using AP5, blocks the formation of LTP.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
« previous next »
 

Did you know?

Barbituric acid, the base material of barbiturates, was first synthesized in 1863 by Adolph von Bayer. His company later went on to synthesize aspirin for the first time, and Bayer aspirin is still a popular brand today.

Did you know?

ACTH levels are normally highest in the early morning (between 6 and 8 A.M.) and lowest in the evening (between 6 and 11 P.M.). Therefore, a doctor who suspects abnormal levels looks for low ACTH in the morning and high ACTH in the evening.

Did you know?

The eye muscles are the most active muscles in the whole body. The external muscles that move the eyes are the strongest muscles in the human body for the job they have to do. They are 100 times more powerful than they need to be.

Did you know?

In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.

Did you know?

Vampire bats have a natural anticoagulant in their saliva that permits continuous bleeding after they painlessly open a wound with their incisors. This capillary blood does not cause any significant blood loss to their victims.

The size of the antlers play a significant role in establishing the hierarchy in the group The size of the antlers play a significant role in establishing the hierarchy in the group
A Midsagittal View of the Brain and Part of the Spinal Cord A Midsagittal View of the Brain and Part of the Spinal Cord
Emotional Pathways in the Brain Emotional Pathways in the Brain
Scanning the Brain Scanning the Brain
The Adolescent Brain and Schizophrenia The Adolescent Brain and Schizophrenia
Topographical maps of the brain of dogs Topographical maps of the brain of dogs
Video: Coronary Heart Disease

For a complete list of videos, visit our video library