One mechanism for the tolerance produced by repeated drug ...

[jerry coleman]

One mechanism for the tolerance produced by repeated drug administration is a(n)
 
  a. decreased metabolism of the drug.
  b. increased plasma level of the drug.
  c. increased number of receptors in the brain.
  d. reduced number of receptors for the drug.
  e. increased number of ion channel openings in response to receptor activation.

Question 2

After two years, Sam needs to smoke more cigarettes to achieve the same feelings as he had when he first started smoking. This need to increase dosage is due to
 
  a. dynamic capacity.
  b. sensitization.
  c. inactivation.
  d. tolerance.
  e. binding capacity.

[leeeep]

Answer to Question 1

Answer: d. a reduced number of receptors for the drug.

Answer to Question 2

Answer: d. tolerance.