A stomach cell is producing pepsin, an enzyme that hydrolyzes proteins. Which of the following events suggests that gene expression of pepsin has been turned off in the cell?
◦ The chromosome with the pepsin gene is tightly coiled.
◦ Activators and RNA polymerases are abundant in the nucleus.
◦ The pepsin mRNA leaves the nucleus and enters the cytoplasm.
◦ The pepsin protein is folded properly in the cytoplasm.