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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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Computer programs are available that crosscheck a new drug's possible trade name with all other trade names currently available. These programs detect dangerous similarities between names and alert the manufacturer of the drug.
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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.
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Sildenafil (Viagra®) has two actions that may be of consequence in patients with heart disease. It can lower the blood pressure, and it can interact with nitrates. It should never be used in patients who are taking nitrates.