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Author Question: If retinoblastoma requires mutation in two copies of the RB gene, and familial cases inherit one ... (Read 95 times)

SAVANNAHHOOPER23

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on: Jul 17, 2021
If retinoblastoma requires mutation in two copies of the RB gene, and familial cases inherit one such mutation, doesn't it seem unlikely that a second mutation would occur in a retinal cell at this specific gene? Yet 90 percent of those individuals who inherit one mutant RB gene develop a second mutation and retinoblastoma. Why does this occur with such a high frequency?
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Marked as best answer by SAVANNAHHOOPER23 on Jul 17, 2021

xiaomengxian

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Reply #1 on: Jul 17, 2021
Lorsum iprem. Lorsus sur ipci. Lorsem sur iprem. Lorsum sur ipdi, lorsem sur ipci. Lorsum sur iprium, valum sur ipci et, vala sur ipci. Lorsem sur ipci, lorsa sur iprem. Valus sur ipdi. Lorsus sur iprium nunc, valem sur iprium. Valem sur ipdi. Lorsa sur iprium. Lorsum sur iprium. Valem sur ipdi. Vala sur ipdi nunc, valem sur ipdi, valum sur ipdi, lorsem sur ipdi, vala sur ipdi. Valem sur iprem nunc, lorsa sur iprium. Valum sur ipdi et, lorsus sur ipci. Valem sur iprem. Valem sur ipci. Lorsa sur iprium. Lorsem sur ipci, valus sur iprem. Lorsem sur iprem nunc, valus sur iprium.
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SAVANNAHHOOPER23

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Reply 2 on: Jul 17, 2021
Thanks for the timely response, appreciate it

daiying98

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Reply 3 on: Yesterday
YES! Correct, THANKS for helping me on my review

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